Fat redistribution is a side effect of some antiretroviral drugs. It describes redistributing fat in the body and hence changing the body shape.
Fat loss often occurs underneath the skin in the cheeks, buttocks, arms, legs and soles of feet. Meanwhile fat accumulates at the back of the neck, abdomen and breasts. The pattern and severity of body fat changes might be different for different people. Fat redistribution is different from muscle loss.
Quite often people with HIV will experience both fat loss and accumulation, so the body weight might not be altered. However, such changes in the body shape might affect people's ability to perform daily activities such as moving around, walking, sitting and sleeping.